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膝关节和脊柱粒细胞肉瘤作为儿童急性髓性白血病的无白血病复发

Granulocytic sarcoma of the knee and the spine as aleukemic relapse of acute myeloid leukemia in a child.

作者信息

Masetti Riccardo, Gasperini Pietro, Prete Arcangelo, Pession Andrea

机构信息

Paediatric Oncology and Haematology Unit Lalla Seràgnoli, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

出版信息

J Pediatr Hematol Oncol. 2011 Aug;33(6):480-1. doi: 10.1097/MPH.0b013e3181faf8b0.

Abstract

Granulocytic sarcoma is a very rare disease in childhood, which may precede the clinical manifestations of acute myeloid leukemia or may occur as a relapse of a nonleukemic acute myeloid leukemia. It is a malignant, solid tumor consisting of myeloblasts or immature myeloid cells occurring in extramedullary sites. We report interesting magnetic resonance images of a nonleukemic relapse of acute myeloid leukemia in a child presenting as a granulocytic sarcoma unusually localized to the knee and spine.

摘要

粒细胞肉瘤是一种儿童期非常罕见的疾病,它可能先于急性髓系白血病的临床表现出现,也可能作为非白血病性急性髓系白血病的复发而发生。它是一种恶性实体瘤,由发生于髓外部位的成髓细胞或未成熟髓系细胞组成。我们报告了一名儿童急性髓系白血病非白血病性复发的有趣磁共振图像,该复发表现为粒细胞肉瘤,异常定位于膝关节和脊柱。

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