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脓毒症和脓毒性休克的抗菌治疗——两药联用是否优于单药?

Antimicrobial therapy of sepsis and septic shock--when are two drugs better than one?

机构信息

Department of Internal Medicine, Section of Infectious Diseases, University of Wisconsin Hospital and Clinics, 1685 Highland Avenue, Madison, WI 53705, USA.

出版信息

Crit Care Clin. 2011 Apr;27(2):e1-27. doi: 10.1016/j.ccc.2010.12.001.

Abstract

In clinical practice, physicians frequently use combination therapy despite the conflicting evidence for its effectiveness. The results of recent studies have contributed to our understanding of this important issue. In this article, we examine the evidence for, or against, the use of combination drug therapy compared with monotherapy in the management of serious infections, sepsis, and septic shock.

摘要

在临床实践中,尽管联合治疗的有效性存在争议,但医生经常会使用联合治疗。最近的研究结果有助于我们了解这个重要问题。本文探讨了严重感染、脓毒症和感染性休克的管理中,与单药治疗相比,联合药物治疗的证据是支持还是反对。

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