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炎症性和非炎症性血管疾病导致的胆血症。

Inflammatory and noninflammatory vascular disease causing hemobilia.

机构信息

Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

出版信息

J Clin Rheumatol. 2011 Apr;17(3):138-41. doi: 10.1097/RHU.0b013e318214ef95.

Abstract

Typical angiographic finding of polyarteritis nodosa (PAN) shows aneurysms in small- and medium-size arteries, which can assist in diagnosis. Mimics of vasculitis share similar angiographic and clinical manifestations with PAN, making diagnosis confusing. We report 2 patients admitted with hemobilia, one of whom had vasculitis and case of the other mimicked vasculitis.The first patient was an 18-year-old man with epigastric pain. On serial workup, hemobilia with multiple hepatic artery aneurysms was diagnosed and embolized. Later, PAN was confirmed on pathologic examination of gallbladder after cholecystectomy.Second patient was an 18-year-old woman also with epigastric pain. Serial workup revealed multiple microaneurysms of the hepatic artery without bleeding, but 4 days later, fistula between hepatic artery and bile duct was found, and embolization was performed. She was readmitted 1 month later because of hemorrhage of gallbladder, and pathologic examination of gallbladder showed evidence of fibromuscular dysplasia.Clinicians should be aware of mimics of vasculitis when diagnosing gastrointestinal involvement of vasculitis.

摘要

结节性多动脉炎(PAN)的典型血管造影表现为小、中动脉的动脉瘤,有助于诊断。血管炎的类似物与 PAN 具有相似的血管造影和临床表现,导致诊断混淆。我们报告了 2 例因血胆症入院的患者,其中 1 例患有血管炎,另 1 例为血管炎类似物。第一例患者是一名 18 岁男性,有上腹痛。连续检查发现多发性肝动脉瘤伴血胆症,并进行了栓塞。后来,在胆囊切除术后胆囊的病理检查中确诊为 PAN。第二例患者也是一名 18 岁女性,同样有上腹痛。连续检查显示肝动脉多发微小动脉瘤但无出血,但 4 天后发现肝动脉和胆管之间有瘘管,进行了栓塞。1 个月后,她因胆囊出血再次入院,胆囊的病理检查显示纤维肌性发育不良的证据。临床医生在诊断血管炎的胃肠道受累时应注意血管炎的类似物。

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