Department of Psychiatry & Behavioral Sciences, University of California, Davis, Davis, CA, USA.
J Autism Dev Disord. 2012 Jan;42(1):48-59. doi: 10.1007/s10803-011-1215-z.
Findings regarding phenotypic differences between boys and girls with ASD are mixed. We compared autism and internalizing symptoms in a sample of 8-18 year-old girls (n = 20) and boys (n = 20) with ASD and typically developing (TYP) girls (n = 19) and boys (n = 17). Girls with ASD were more impaired than TYP girls but did not differ from boys with ASD in autism symptoms. In adolescence, girls with ASD had higher internalizing symptoms than boys with ASD and TYP girls, and higher symptoms of depression than TYP girls. Girls ages 8-18 with ASD resemble boys with ASD and not TYP girls, and appear to be at increased risk for affective symptoms in the teen years.
关于 ASD 男童和女童之间表型差异的研究结果不一。我们在一个 8-18 岁的 ASD 女童(n=20)和男童(n=20)样本中,以及在 ASD 女童(n=19)和男童(n=17)的典型发育(TYP)女童和男童中比较了自闭症和内化症状。患有 ASD 的女童比 TYP 女童受损更严重,但自闭症症状与 ASD 男童无差异。在青春期,患有 ASD 的女童比患有 ASD 的男童和 TYP 女童有更高的内化症状,比 TYP 女童有更高的抑郁症状。8-18 岁患有 ASD 的女童与 ASD 男童相似,而与 TYP 女童不同,并且在青少年时期似乎有更高的情感症状风险。