Department of Neuroanaesthesia and Neurointensive Care, The Walton Centre of Neurosciences, Liverpool, UK.
Neurocrit Care. 2011 Dec;15(3):525-8. doi: 10.1007/s12028-011-9529-4.
Sustained severe hyperthermia in patients with high cervical spinal cord injuries may have many etiologies, from infection to autonomic dysregulation. When uncontrolled, it has been seen to have a high morbidity and mortality.
We present two patients with high cervical spinal cord injury (SCI) who had sustained severe hyperpyrexia, of possible autonomic origin. The temperature stayed above 40°C and was uncontrolled with conventional methods of temperature management.
We employed endovascular cooling for therapeutic normothermia which was successful in effective control of temperature in both the patients. The first patient suffered complications from deep vein thrombosis and pulmonary embolism which may be attributed to the presence of the cooling catheter in spite of chemical and mechanical thromboprophylaxis.
The use of endovascular cooling in the management of severe life threatening hyperthermia in patients with cervical SCI may be an useful intervention. There must be a high suspicion for the possibility of deep vein thrombosis in this subgroup, however.
高位颈髓损伤患者持续严重高热可能有多种病因,从感染到自主神经功能失调。如果得不到控制,其发病率和死亡率会很高。
我们介绍了两名高位颈髓损伤(SCI)患者,他们出现了可能由自主神经功能失调引起的严重高热。体温持续高于 40°C,常规体温管理方法无法控制。
我们采用血管内冷却进行治疗性体温正常化,这在两名患者中均成功有效地控制了体温。第一位患者出现了深静脉血栓形成和肺栓塞的并发症,这可能与冷却导管的存在有关,尽管进行了化学和机械血栓预防。
在治疗颈 SCI 患者严重危及生命的高热时,血管内冷却的使用可能是一种有用的干预措施。然而,对于该亚组,必须高度怀疑深静脉血栓形成的可能性。