Helske Satu, Kupari Markku
HYKS:n kardiologian klinikka, HUS.
Duodecim. 2011;127(1):35-42.
The disease condition underlying the stenosis of the aortic valve resembles atherosclerosis and is dominated by activation of inflammatory cells, and accumulation of cholesterol and involves progressive fibrosis and calcification. Stenosis of the aortic valve may remain asymptomatic for long. Characteristic symptoms include exertional dyspnea and asthenia, angina pectoris type chest pain or loss of consciousness on exertion. The essential clinical finding on examination is a systolic murmur of the heart. Doppler ultrasonography of the heart is the diagnostic cornerstone. Stenosis of the aortic valve is treated with prosthetic valve surgery.
主动脉瓣狭窄的潜在疾病状况类似于动脉粥样硬化，以炎症细胞激活、胆固醇积聚为主，并涉及进行性纤维化和钙化。主动脉瓣狭窄可能长期无症状。典型症状包括劳力性呼吸困难、乏力、心绞痛样胸痛或劳力时意识丧失。检查的主要临床发现是心脏收缩期杂音。心脏多普勒超声检查是诊断的基石。主动脉瓣狭窄采用人工瓣膜手术治疗。
