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皮肤老化的纵向研究:从微观起伏到皱纹。

Longitudinal study of skin aging: from microrelief to wrinkles.

机构信息

L'Oréal Recherche, Chevilly Larue, France Consultant, Paris, France.

出版信息

Skin Res Technol. 2011 May;17(2):135-40. doi: 10.1111/j.1600-0846.2010.00481.x.

DOI:10.1111/j.1600-0846.2010.00481.x
PMID:21443743
Abstract

AIM

To study the changes in skin microrelief and periocular wrinkles during the aging process.

METHODS

Replicas of the crow's feet area of volunteers were recorded in 1987 and 2008 and observed comparatively. Characteristic features were quantified by image analysis.

RESULTS

Observation shows that some microrelief features disappear and even merge with wrinkles that become more marked. Some primary lines also tend to merge to form thin new wrinkles. Quantitative data support these observations: the size of small and medium objects of skin relief decreases with age while large objects are becoming larger.

CONCLUSION

Over 21 years, in the group studied, the total area of the detected objects remains quite constant. Only the distribution between small and large detected objects (microrelief features and wrinkles, respectively) is modified.

摘要

目的

研究皮肤微观结构和眼周皱纹在衰老过程中的变化。

方法

1987 年和 2008 年分别对志愿者鱼尾纹部位的复制品进行记录,并进行比较观察。通过图像分析对特征进行定量。

结果

观察表明,一些微观结构特征消失,甚至与变得更加明显的皱纹融合。一些最初的线也趋于融合形成新的细皱纹。定量数据支持这些观察结果:皮肤纹理的小和中等物体的大小随年龄增长而减小,而大物体则变得更大。

结论

在 21 年的时间里,在所研究的人群中,检测到的物体的总面积保持相当稳定。只有小物体和大物体(分别为微观结构特征和皱纹)之间的分布发生了变化。

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