代谢性肌病：临床特征和诊断方法。

Metabolic myopathies: clinical features and diagnostic approach.

机构信息

Division of Pediatric Neurology, Department of Pediatrics, Duke University Medical Center, DUMC Box 3936, Durham, NC 27710, USA.

出版信息

Rheum Dis Clin North Am. 2011 May;37(2):201-17, vi. doi: 10.1016/j.rdc.2011.01.004.

DOI:10.1016/j.rdc.2011.01.004

PMID:21444020

Abstract

The rheumatologist is frequently called on to evaluate patients with complaints of myalgia, muscle cramps, and fatigue. The evaluation of these patients presents a diagnostic challenge given the nonspecific and intermittent nature of their complaints, often leading to inappropriate diagnostic testing. When these symptoms are associated with physical exertion, a metabolic myopathy should be suspected Although inflammatory myopathies may present with similar features, such a pattern should prompt a thorough evaluation for an underlying metabolic myopathy. This review discusses the most common causes of metabolic myopathies and reviews the current diagnostic options available to the clinician.

摘要

风湿科医生经常需要评估出现肌肉疼痛、肌肉痉挛和疲劳等症状的患者。由于这些患者的症状具有非特异性和间歇性，通常导致不合适的诊断性检查，因此评估这些患者具有一定的挑战性。当这些症状与体力活动有关时，应怀疑代谢性肌病。虽然炎症性肌病也可能出现类似的特征，但这种模式应促使对潜在代谢性肌病进行彻底评估。本综述讨论了最常见的代谢性肌病的病因，并回顾了临床医生目前可用的诊断选择。