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腹腔内脾组织假性转移瘤,酷似转移性癌。

Intra-abdominal splenosis mimicking metastatic cancer.

机构信息

Department of Hematology/Oncology, Baylor College of Medicine, Houston, Texas 77030, USA.

出版信息

Am J Med Sci. 2011 Mar;341(3):246-9. doi: 10.1097/maj.0b013e318202893f.

DOI:10.1097/maj.0b013e318202893f
PMID:21446083
Abstract

Splenosis, the heterotopic autotransplantion of splenic tissue, is a common benign condition among patients with a history of splenic trauma. Most cases of splenosis are intra-abdominal due to direct seeding of surrounding structures, although these ectopic rests may occur almost anywhere in the body, and its diffuse nature may raise the suspicion of metastatic cancer. Confirmation of splenic tissue can be made by technetium-99m (Tc-99m) sulfur colloid scintigraphy or with Tc-99m heat-damaged red blood cells; however, in some cases, biopsy may be required for definitive diagnosis. Here, the authors present a patient with a remote history of posttraumatic splenectomy who was discovered to have multiple intra-abdominal nodules by CT scan. A diagnosis of diffuse metastatic disease was initially considered before a diagnosis of intraabdominal splenosis was ultimately made with the aid of Tc-99m sulfur colloid single-positron emission computed tomography (SPECT) and computed tomography imaging.

摘要

脾组织的异位自体移植,即脾种植,是有脾外伤史患者中一种常见的良性病变。大多数脾种植病例位于腹腔内,是由于周围结构的直接播种所致,尽管这些异位残余组织可能出现在身体的任何部位,而且其弥漫性特征可能会引起转移性癌症的怀疑。脾组织的确认可通过锝-99m(Tc-99m)硫胶体闪烁扫描或 Tc-99m 热损伤的红细胞来实现;然而,在某些情况下,为了明确诊断可能需要进行活检。在这里,作者介绍了一位有远处脾切除外伤史的患者,其 CT 扫描发现多个腹腔内结节。最初考虑为弥漫性转移疾病的诊断,然后在 Tc-99m 硫胶体单光子发射计算机断层扫描(SPECT)和计算机断层成像的帮助下,最终诊断为腹腔内脾种植。

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Am J Med Sci. 2011 Mar;341(3):246-9. doi: 10.1097/maj.0b013e318202893f.
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