Al-Shaham A A, Samher A A
Department of Surgery, International Medical School, Management and Science University, Shah Alam-Selangor, Malaysia.
J Plast Surg Hand Surg. 2010 Dec;44(6):318-21. doi: 10.3109/02844311003683713.
Despite the fact that cemento-ossifying fibromas of the maxilla may be quite large and locally aggressive, en-bloc excision is achieved by gentle blunt dissection, with the whole tumour mass peeled out from the adjacent structures. Until recently different fibro-osseous tumours that contained cementum were classified together as "cementomas". In 1992 The World Health Organization adopted a new classification that included these fibromas as benign osseous tumours. While such tumours of the mandible are common, those of the maxilla are rare. They are growth products of periodontal membrane remnant. The triggering mechanism in the formation of cementum outside the periodontal membrane remains unclear. We present a 35-year-old woman who had a giant expanding lobular mass in the right maxilla of 5 years duration. She had visual disturbances and nasal obstruction, and was treated successfully by surgical en-bloc resection of the tumour through an infraorbital transverse incision. The differential diagnosis included fibrous dysplasia, osteoid osteoma, osteoblastoma, chronic sclerosing osteomyelitis, ameloblastoma, squamous cell carcinoma of the maxillary sinus, calcifying epithelial odontogenic tumour (Pindborg tumour) and calcifying odontogenic cyst (Gorlin cyst). Histopathological examination confirmed a cemento-ossifying fibroma.
尽管上颌骨的骨化纤维瘤可能体积相当大且具有局部侵袭性,但通过轻柔的钝性分离可实现整块切除,将整个肿瘤块从相邻结构中剥离出来。直到最近,不同的含牙骨质纤维骨性肿瘤都被归类为“牙骨质瘤”。1992年,世界卫生组织采用了一种新的分类方法,将这些纤维瘤列为良性骨肿瘤。虽然下颌骨的此类肿瘤很常见,但上颌骨的却很罕见。它们是牙周膜残余的生长产物。牙周膜外牙骨质形成的触发机制仍不清楚。我们报告一位35岁女性,其右上颌骨有一个持续5年的巨大、膨胀性分叶状肿物。她有视觉障碍和鼻塞症状,通过经眶下横切口对肿瘤进行手术整块切除而成功治愈。鉴别诊断包括骨纤维异常增殖症、骨样骨瘤、成骨细胞瘤、慢性硬化性骨髓炎、成釉细胞瘤、上颌窦鳞状细胞癌、钙化上皮性牙源性肿瘤(平德博尔格瘤)和钙化牙源性囊肿(戈林囊肿)。组织病理学检查证实为骨化纤维瘤。