全层角膜“通气切口”：上皮穿透多深？
Full-thickness corneal "vent incisions": how deep does the epithelium penetrate?
机构信息
Department of Ophthalmology, Albert Einstein College of Medicine, North Shore-Long Island Jewish Health System, Great Neck, NY, USA.
出版信息
Cornea. 2011 Jul;30(7):804-6. doi: 10.1097/ICO.0b013e3181d527b1.
PURPOSE
To evaluate epithelial cell penetration produced by full-thickness "vent incisions."
METHODS
Six donor human corneas with intact epithelium were placed on an artificial anterior chamber. Four perforating paracentral vent incisions were made in each cornea using a diamond knife.
RESULTS
Twenty incisions were analyzed. Of the 20 wounds, 9 (45%) wounds demonstrated introduction of epithelial cells. Of these, 8 (89%) had epithelial cells at the level of the anterior half of the stroma, 3 (33%) had cells at the level of the posterior half of the stroma, and 1 (11%) had cells on the endothelium.
CONCLUSIONS
Full-thickness vent incisions, as performed with Descemet stripping automated endothelial keratoplasty, introduced epithelium into the stroma as deep as the endothelium. This may prove a source of epithelial ingrowth.
目的
评估全层“通气切口”产生的上皮细胞穿透作用。
方法
将 6 个带有完整上皮的供体人角膜置于人工前房上。使用金刚石刀在每个角膜上制作 4 个穿透性旁中央通气切口。
结果
分析了 20 个切口。在 20 个伤口中，有 9 个（45%）伤口显示出上皮细胞的引入。其中，8 个（89%）在前基质的前半部分有上皮细胞，3 个（33%）在后基质的后半部分有细胞，1 个（11%）在角膜内皮上有细胞。
结论
用 Descemet 剥离自动内皮角膜移植术进行的全层通气切口将上皮细胞引入到与内皮一样深的基质中。这可能证明是上皮内长的来源。
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