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癫痫的病因分类。

The etiologic classification of epilepsy.

机构信息

UCL Institute of Neurology, University College London, Queen Square, London, UK.

出版信息

Epilepsia. 2011 Jun;52(6):1052-7. doi: 10.1111/j.1528-1167.2011.03041.x. Epub 2011 Mar 30.

DOI:10.1111/j.1528-1167.2011.03041.x
PMID:21449936
Abstract

The etiology of epilepsy is a major determinant of clinical course and prognosis, yet the current classifications of epilepsy do not list etiology in any detail. In this article, a classification (database) of the etiologies of epilepsy is proposed. In this scheme, the etiology of epilepsy is divided into four categories: idiopathic, symptomatic, provoked, and cryptogenic. These are defined and subcategories are proposed. A commentary addressing the following points is included: problems associated with assigning causation, symptomatic versus idiopathic epilepsy, focal versus generalized epilepsy, acquired epilepsy, acute symptomatic epilepsy, risk factor analysis, provoked epilepsy genetic and developmental epilepsy, and epilepsy as a disease not a symptom.

摘要

癫痫的病因是临床病程和预后的主要决定因素,但目前的癫痫分类并未详细列出病因。本文提出了一种癫痫病因分类(数据库)。在该方案中,癫痫的病因分为四个类别:特发性、症状性、诱发性和隐源性。对这些类别进行了定义并提出了亚类。包括以下内容的评论:与因果关系分配相关的问题、症状性与特发性癫痫、局灶性与全面性癫痫、获得性癫痫、急性症状性癫痫、风险因素分析、诱发性癫痫、遗传和发育性癫痫、以及癫痫作为一种疾病而非一种症状。

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The etiologic classification of epilepsy.癫痫的病因分类。
Epilepsia. 2011 Jun;52(6):1052-7. doi: 10.1111/j.1528-1167.2011.03041.x. Epub 2011 Mar 30.
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Clinical investigation of genetic contributions to childhood-onset epilepsies and epileptic syndromes.儿童期癫痫及癫痫综合征遗传因素的临床研究。
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One-year mortality in Bordeaux cohort: the value of syndrome classification.波尔多队列中的一年死亡率:综合征分类的价值。
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