School of Dentistry, Division of Periodontics, University of São Paulo, São Paulo, Brazil.
J Clin Periodontol. 2011 Jul;38(7):637-43. doi: 10.1111/j.1600-051X.2011.01725.x. Epub 2011 Mar 30.
To evaluate the clinical efficacy of subgingival ultrasonic instrumentation irrigated with essential oils (EOs) of residual periodontal pockets.
Sixty-four individuals with chronic periodontitis were invited to participate in this randomized, double-blind, parallel, and placebo-controlled clinical trial. All subjects received non-surgical periodontal therapy. After re-evaluation (baseline), residual pockets (pocket depth ≥5 mm) received test (ultrasonic instrumentation irrigated with EOs) or control therapy (ultrasonic instrumentation irrigated with negative control). Probing pocket depth (PPD), gingival recession (R), clinical attachment level (CAL), bleeding on probing (BOP), and plaque were assessed at baseline and after 4, 12, and 24 weeks. Differences between groups and changes over the course of time were analysed according to a generalized linear model.
There was a significant reduction in PPD and BOP, as well as a significant CAL gain in the two groups (p<0.001). Nevertheless, there were no differences between the groups at any time of the study. When only initially deep pockets (PPD ≥7 mm) were analysed, a significantly greater CAL gain (p=0.03) and PPD reduction (p=0.01) was observed in the test group.
The adjunctive use of EOs may promote significant CAL gain and PPD reduction in deep residual pockets.
评估龈下超声器械冲洗牙周袋残留部位的精油（EOs）的临床疗效。
邀请 64 名慢性牙周炎患者参加这项随机、双盲、平行、安慰剂对照的临床试验。所有受试者均接受非手术牙周治疗。在重新评估（基线）后，残留袋（袋深≥5mm）接受试验（超声器械冲洗 EOs）或对照治疗（超声器械冲洗阴性对照）。在基线和 4、12 和 24 周时评估探诊袋深度（PPD）、牙龈退缩（R）、临床附着水平（CAL）、探诊出血（BOP）和菌斑。根据广义线性模型分析组间差异和随时间的变化。
两组的 PPD 和 BOP 均显著降低，CAL 均显著增加（p<0.001）。然而，在研究的任何时间点，两组之间均无差异。当仅分析最初的深袋（PPD≥7mm）时，试验组的 CAL 增加（p=0.03）和 PPD 减少（p=0.01）更为显著。
EOs 的辅助使用可能会促进深残留袋的 CAL 显著增加和 PPD 减少。
