Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania School of Medicine, 3400 Civic Center, Philadelphia, PA 19104, USA.
Curr Opin Cardiol. 2011 May;26(3):256-60. doi: 10.1097/HCO.0b013e328345af65.
Significant technological advances have occurred in mechanical assist devices over the past decade. With improving hemodynamics and durability, ventricular assist devices (VADs) are being implanted with increasing frequency. Yet, several VAD-specific morbidities and technological challenges, which are reviewed, continue to limit the number of devices that are currently implanted.
We are beginning to understand the pathophysiology of complications specific to continuous-flow VADs, including bleeding and aortic insufficiency. Improved outcomes and durability with currently available continuous-flow VADs are evident, as compared with first-generation devices. A focus on enhancing quality of life with a VAD will be critical to widespread application of mechanical circulatory support to the heart failure patient population.
Advances in technology and surgical technique are continuing to minimize morbidity and mortality associated with mechanical assist devices. Continued technological advancements will allow increased utilization of mechanical circulatory support over the next decade.
在过去的十年中，机械辅助设备取得了重大技术进步。随着血液动力学和耐用性的提高，心室辅助设备（VAD）的植入频率也在不断增加。然而，一些 VAD 特有的并发症和技术挑战仍在限制目前可植入设备的数量。
我们开始了解特定于连续流动 VAD 的并发症的病理生理学，包括出血和主动脉瓣关闭不全。与第一代设备相比，目前可用的连续流动 VAD 的结果和耐用性得到了显著改善。关注 VAD 对生活质量的提高对于将机械循环支持广泛应用于心衰患者群体至关重要。
技术和手术技术的进步继续将与机械辅助设备相关的发病率和死亡率降至最低。在未来十年中，持续的技术进步将允许更多地使用机械循环支持。
