Organisch-Chemisches Institut, Ruprecht-Karls Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
Chem Commun (Camb). 2011 Jun 21;47(23):6536-44. doi: 10.1039/c1cc10780a. Epub 2011 Mar 31.
The article reviews the most important developments in the synthesis of heterocycles by gold catalysts for reactions directly involving the heteroatoms in the reacting groups. Reactions without direct participation of the hetero atoms, for example in substrates with the heteroatom in a tether between the reacting groups, are not included. In the last decade homogeneous gold catalysis has emerged from a handful of scattered publications to a hot topic, an area with now hundreds of publications per year. Among the many different products accessible by the new methods developed, heterocycles are probably the most important class of compounds with significant impact on the synthesis of agrochemicals and pharmaceuticals.
本文综述了通过金催化剂直接参与反应基团中杂原子的杂环合成的最重要进展。不包括不直接参与杂原子的反应，例如在具有杂原子的连接基团之间的底物中。在过去的十年中，均相金催化已经从少数分散的出版物发展成为一个热门话题，每年有数百篇出版物的领域。在所开发的许多不同的方法中，杂环化合物可能是最重要的一类化合物，对农用化学品和药物的合成有重要影响。
