氨基酸前体的次生分解：氰化氢聚合物作为蛋白质祖先的证据。

Deuterolysis of amino acid precursors: evidence for hydrogen cyanide polymers as protein ancestors.

作者信息

Matthews C, Nelson J, Varma P, Minard R

出版信息

Science. 1977 Nov 11;198(4317):622-5. doi: 10.1126/science.21452.

Abstract

Deuterolysis experiments suggest that hydrogen cyanide polymers rather than aminoacetonitriles are major precursors of alpha-amino acids obtained from spark reactions and other studies on chemical evolution. These results are consistent with the hypothesis that the original heteropolypeptides on the earth were synthesized spontaneously from hydrogen cyanide and water without the intervening formation of alpha-amino acids.

摘要

氘解实验表明，从火花放电反应以及其他关于化学进化的研究中得到的α-氨基酸的主要前体是氰化氢聚合物而非氨基乙腈。这些结果与以下假说一致：地球上最初的杂多肽是由氰化氢和水自发合成的，中间没有α-氨基酸的形成过程。