Department of Medicine, University of Cincinnati, Cincinnati, OH 45226, USA.
Mol Cell Endocrinol. 2011 Jun 20;340(1):29-34. doi: 10.1016/j.mce.2011.03.001. Epub 2011 Mar 29.
Ghrelin is the only known circulating hormone that acts on peripheral and central targets to increase food intake and promote adiposity. The present review focuses on the possible clinical relevance of ghrelin in the regulation of human feeding behavior in individuals with obesity and other eating disorders such as Prader-Willi syndrome, anorexia nervosa, bulimia nervosa and binge-eating.
胃饥饿素是唯一已知的作用于外周和中枢靶点以增加食物摄入并促进肥胖的循环激素。本综述重点介绍了胃饥饿素在调节肥胖人群和其他进食障碍（如普拉德-威利综合征、神经性厌食症、神经性贪食症和暴食症）患者的人类摄食行为方面的可能临床意义。
