HealthPartners Research Foundation, Bloomington, MN 55425, USA.
Contemp Clin Trials. 2011 Jul;32(4):551-60. doi: 10.1016/j.cct.2011.03.011. Epub 2011 Mar 29.
Long-term weight-loss maintenance is notoriously difficult to achieve and promote. As the novelty of weight loss treatment fades, enthusiasm for diet and exercise tends to wane in the maintenance phase. Given the recognition of obesity as a chronic disorder requiring continued engagement in weight-control behaviors, there is a need to identify cost-effective and supportive therapies that can sustain motivation. In this paper, we describe the study design and baseline characteristics of participants enrolled in a trial to evaluate a program (Keep It Off) developed specifically for weight-loss maintenance using therapeutic phone contact with recent weight losers throughout the period in which they are at highest risk for weight regain. In the Keep It Off randomized clinical trial we are evaluating this phone-based intervention that focuses on key weight-loss maintenance behaviors followed by continued self-monitoring, reporting of weight, feedback, and outreach in members of a Minnesota managed-care organization. The goal of the intervention is to flatten the typical relapse curve. Moreover, data from this trial will inform our understanding of weight-loss maintenance, including predictors and behaviors that increase the likelihood of success over the long term.
长期的体重减轻维持是众所周知的难以实现和促进的。随着减肥治疗的新奇感逐渐消失，在维持阶段，人们对饮食和运动的热情往往会减弱。鉴于肥胖被认为是一种需要持续参与体重控制行为的慢性疾病，因此有必要确定具有成本效益且支持性的治疗方法，以维持动机。在本文中，我们描述了一项试验的研究设计和参与者的基线特征，该试验旨在评估一个专门为减肥维持而开发的计划（保持体重），该计划使用治疗性电话联系最近减肥者，在他们体重最容易反弹的时期内，一直使用这种方式。在 Keep It Off 随机临床试验中，我们正在评估这种基于电话的干预措施，该措施侧重于关键的减肥维持行为，然后是持续的自我监测、体重报告、反馈和在明尼苏达州管理式医疗组织成员中的外展。干预的目标是使典型的复发曲线变平。此外，这项试验的数据将为我们理解减肥维持提供信息，包括长期成功的预测因素和行为。
