Joffre F, Nomblot C, Bartoli J M, Rousseau H, Cécile J P, Kasbarian M, Gaux J C, Bodenard M, Lyonnet D
Services de radiologie, CHU Rangueil, Toulouse.
J Mal Vasc. 1990;15(3):239-44.
MATERIALS AND METHODS. A multicenter study was undertaken to determine the long-term results of renal angioplasty. Five teams with considerable experience in the procedure replied to a computerized questionnaire concerning transluminal angioplasty (TLA) performed with immediate success from 1979 to 1985 and followed up regularly (minimum of four years). The main purpose of the study was to assess the long-term results, both anatomical results and clinical, of renal TLA. Consideration was given to anatomical of average quality and their possible correlation with long-term results, in an attempt to foresee and even prevent restenosis. The main points of the study are given in figure 1. Two hundred and forty-seven renal TLA performed in 210 patients were included (insofar as clinical and radiologic follow-up was adequate, with a minimum of one control angiography beyond six months). Patients who had immediate failure (dilatation not possible or ineffective dilatation) were excluded from the analysis of long-term results. Likewise, TLA of the renal artery of grafted kidneys were not included in this study. The histogram of patients ages shows a clear predominance of subjects 60 to 65 years of age, with extremes ranging from 10 to 80 years (mean 53 years). TLA were done mainly by the femoral route according to a technique using a balloon catheter positioned on a previously inserted guide at the level of the stenosis. The examination was performed under local anesthesia. Balloon size was determined according to the diameter of the renal artery upstream from the stenosis and that of the contralateral renal artery. A balloon of the same or slightly larger caliber was used. The indication of angioplasty was determined after multidisciplinary discussion according to two main criteria: First, treatment of hypertension presumed to be in relation with a stenosis of the renal artery (renovascular hypertension). Secondly, conservation of the nephrotic capacities of a patient with a renal stenosis possibly associated with arterial hypertension, in relation with a bilateral stenosis of the renal arteries or with a unilateral stenosis affecting a functionally or anatomically single kidney. In this latter case, the purpose of TLA was to avoid development toward thrombosis of the renal artery and worsening of renal insufficiency. RESULTS. Two hundred and forty-seven TLA in 210 patients were included in the study. Nineteen patients (9%) had bilateral TLA. The lesions treated are indicated in figure 3. These were most often simple atheromatous and truncal lesions of the renal artery (73%) which were significant (greater than 50%) in 99% of cases. TLA was indicated in 77% of cases for treatment of arterial hypertension presumed to be renovascular. In 23% of cases, treatment of the stenosis was intended to conserve, especially, kidney vascularization, i.e., an indication of nephrotic protection. There were 9.7% immediate failures...
材料与方法。开展了一项多中心研究以确定肾血管成形术的长期结果。五个在该手术方面经验丰富的团队回复了一份关于1979年至1985年期间成功完成的经皮腔内血管成形术(TLA)的计算机化问卷,并进行了定期随访(至少四年)。该研究的主要目的是评估肾TLA的长期结果,包括解剖学结果和临床结果。考虑了平均质量的解剖结构及其与长期结果的可能相关性,试图预见甚至预防再狭窄。研究要点见图1。纳入了210例患者进行的247次肾TLA(只要临床和放射学随访充分,至少在六个月后进行一次对照血管造影)。立即失败(无法扩张或扩张无效)的患者被排除在长期结果分析之外。同样,移植肾肾动脉的TLA不包括在本研究中。患者年龄直方图显示60至65岁的受试者明显占优势,年龄范围从10岁到80岁(平均53岁)。TLA主要通过股动脉途径进行,采用一种技术,即将球囊导管置于先前插入的位于狭窄部位的导丝上。检查在局部麻醉下进行。球囊大小根据狭窄上游肾动脉的直径和对侧肾动脉的直径确定。使用相同或稍大口径的球囊。血管成形术的指征在多学科讨论后根据两个主要标准确定:第一,治疗推测与肾动脉狭窄(肾血管性高血压)相关的高血压。第二,对于可能与动脉高血压相关的肾狭窄患者,在双侧肾动脉狭窄或单侧狭窄影响功能或解剖学上单一肾脏的情况下,保留其肾脏功能。在后一种情况下,TLA的目的是避免肾动脉血栓形成和肾功能不全恶化。结果。210例患者的247次TLA纳入研究。19例患者(9%)进行了双侧TLA。治疗的病变见图3。这些病变最常见的是肾动脉的单纯动脉粥样硬化和主干病变(73%),其中99%的病例病变显著(大于50%)。77%的病例中TLA用于治疗推测为肾血管性的动脉高血压。在23%的病例中,狭窄治疗旨在特别是保留肾脏血管,即肾病保护指征。立即失败率为9.7%……