Division of Asthma, Allergy and Lung Biology, Guy's and St Thomas' National Health Service Foundation Trust, Medical Research Council, London, UK.
Pediatr Clin North Am. 2011 Apr;58(2):481-509, xii. doi: 10.1016/j.pcl.2011.02.002.
Food allergy is a recognized public health concern, for which preventative strategies are required. Although an intervention that adequately protects against the development of food allergy has still to be identified, limited benefits have been shown for the prevention of related allergic conditions such as eczema, and to a lesser extent asthma and rhinitis; these benefits are usually limited to at-risk populations. Prevention strategies need to be tested using randomized controlled study designs that account for the numerous methodological challenges, safety concerns, and necessary ethical limitations.
食物过敏是一个公认的公共卫生问题,需要制定预防策略。尽管还没有发现一种能够充分预防食物过敏发展的干预措施,但已经显示出对预防湿疹等相关过敏疾病(以及在较小程度上预防哮喘和鼻炎)有一定益处;这些益处通常仅限于高危人群。预防策略需要使用随机对照研究设计进行测试,这些设计需要考虑到众多方法学挑战、安全问题和必要的伦理限制。