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[泌尿肿瘤学进展“肿瘤论坛”:2010年精华]

[Advances in uro-oncology "OncoForum": the best of 2010].

作者信息

Gómez-Veiga F, Alcaraz-Asensio A, Burgos-Revilla J, Cózar-Olmo J M

机构信息

Servicio de Urología, Complejo Hospitalario Universitario de A Coruña, La Coruña, España.

出版信息

Actas Urol Esp. 2011 Jun;35(6):315-24. doi: 10.1016/j.acuro.2011.02.001. Epub 2011 Mar 31.

Abstract

OBJECTIVE

To highlight the most important issues of the 2010 annual meetings of the European Association of Urology, EAU), the American Urological Association, AUA, the American Society of Clinical Oncology, ASCO, and the American Society for Therapeutic Radiology and Oncology, ASTRO.

METHODS

A group of experts in oncological urology selected the most important summaries of the four congresses. Subsequently, the revisors assessed the findings in relation to their present and future impact on clinical practice. This document includes the summaries with the highest points.

RESULTS

The following messages were considered important. In pT3 prostate cancer, postoperative radiotherapy (RT) improves local control and biochemical progression-free survival, with no significant impact on distant metastasis and overall survival. In patients with bladder cancer without muscle invasion and with the risk of intermediate recurrence, maintenance chemotherapy does not increase recurrence-free survival after transurethral resection. There is no evidence of a synergist effect of the combination of Temsirolimus/ Bevacizumab in patients with metastatic kidney cell carcinoma without prior treatment. In the SWENOTECA V protocol for the treatment of seminomatous germ-cell testicular cancer, the adjuvant RT was interrupted because the concern regarding the induction of secondary cancers was greater than the reduction of relapses.

CONCLUSIONS

In 2010, new data was produced on the diagnosis and treatment in oncological urology, thanks to the interesting work of different trials.

摘要

目的

突出欧洲泌尿外科学会(EAU)、美国泌尿外科学会(AUA)、美国临床肿瘤学会(ASCO)以及美国放射肿瘤治疗学会(ASTRO)2010年年会的最重要议题。

方法

一组肿瘤泌尿外科学专家挑选了这四个大会的最重要总结。随后,审阅者评估了这些研究结果对当前及未来临床实践的影响。本文档包含得分最高的总结。

结果

以下信息被认为很重要。在pT3期前列腺癌中,术后放疗(RT)可改善局部控制率和无生化进展生存期,对远处转移和总生存期无显著影响。在无肌层浸润且有中度复发风险的膀胱癌患者中,维持化疗并不能提高经尿道切除术后的无复发生存期。对于未经治疗的转移性肾细胞癌患者,尚无证据表明替西罗莫司/贝伐单抗联合使用有协同效应。在SWENOTECA V治疗精原细胞性生殖细胞睾丸癌的方案中,辅助放疗被中断,因为对继发性癌症诱导的担忧大于对复发减少的考量。

结论

由于不同试验的有趣工作,2010年肿瘤泌尿外科学在诊断和治疗方面产生了新数据。

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