Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Bern, Switzerland.
Ann Anat. 2011 May;193(3):185-90. doi: 10.1016/j.aanat.2011.02.006. Epub 2011 Mar 10.
Albrecht von Haller (1708-1777) discovered the infraorbital ethmoid cells, also known as Haller's cells, in 1743. The aim of this historical study is to trace both the different terminology used to name them from the time they were first described anatomically, and the progressive understanding of the role they play in the development of acute rhinosinusitis, and finally to suggest a clear modern definition of Haller's cells based on this history.
A Pubmed search was conducted to find relevant original publications dealing with this subject, and the secondary literature was also reviewed.
Three historical periods can be distinguished in the study of Haller's cells: their initial description in the mid 18th century, followed by a period of obscurity from the mid 18th to the mid 20th century, and finally the modern period starting in the mid 20th century when their clear pathological influence was realized. Haller's cells are thought to contribute to the narrowing of the entrance of the ethmoidal infundibulum and obstruction of the ostium of the maxillary sinus, which could explain the development of rhinosinusitis where inflammation is present.
On the basis of its history, we suggest that the term "Haller's cell" should be restricted to the most inferior infraorbital ethmoid cell, that nearest the ostium of the maxillary sinus.
Albrecht von Haller（1708-1777 年）于 1743 年发现了眶下筛骨细胞，也称为 Haller 细胞。本历史研究旨在追溯从首次解剖描述开始，用于命名这些细胞的不同术语，并逐步了解它们在急性鼻窦炎发展中的作用，最后根据这段历史，为 Haller 细胞提出一个明确的现代定义。
通过 Pubmed 搜索，查找涉及该主题的相关原始出版物，并对二次文献进行综述。
可以将 Haller 细胞的研究分为三个历史时期：它们在 18 世纪中叶的最初描述，随后在 18 世纪中叶至 20 世纪中叶的一个模糊时期，以及 20 世纪中叶开始的现代时期，当时它们的明确病理影响得到了认识。Haller 细胞被认为有助于缩小筛漏斗的入口并阻塞上颌窦的窦口，这可以解释存在炎症时鼻窦炎的发展。
根据其历史，我们建议将“Haller 细胞”一词限制在最靠近上颌窦窦口的最下眶下筛骨细胞。
