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[Significance of sex hormone binding globulin and free androgen index in the estimation of androgenic cases].

作者信息

Qiao F Y, Lauritzen C

机构信息

Abteilung für Gynäkologie und Geburtshilfe, Tongji Hospital, Tongji Medizinische Universität, Wuhan.

出版信息

J Tongji Med Univ. 1990;10(2):124-8. doi: 10.1007/BF02887874.

DOI:10.1007/BF02887874
PMID:2145442
Abstract

Hormone analyses for hirsute women suggested that free testosterone was most revealing in biological effects and sex-hormone-binding globulin (SHBG) was quantitatively persuative. Presented in this paper are the measurements of testosterone, androstendion, dehydroepiandrosterone-sulfate (DHAS), SHBG, androstandiol and free androgen index (FAI) in 51 women with hirsutism. 92% of the hirsute women with elevated androgen level showed decrease in SHBG values and increase in FAI. 17 females with hirsutism revealed abnormally high androstandiol values which were highly related to the values of total and free testosterone (r = 0.78, r = 0.80, respectively). It is suggested that in clinical practice SHBG and FAI should also be measured besides testosterone and DHAS.

摘要

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本文引用的文献

1
[Hyperandrogenemic ovarian insufficiency].
Gynakologe. 1981 Jun;14(2):119-30.
2
Testosterone and androstenedione metabolism in the polycystic ovary syndrome: studies of the percentage binding of testosterone in plasma.多囊卵巢综合征中睾酮和雄烯二酮的代谢:血浆中睾酮结合百分比的研究
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Sex-hormone-binding globulin.性激素结合球蛋白
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Sex-hormone-binding globulin is an oestrogen amplifier.
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