Faculty of Biology, Institute of Biology II, University of Freiburg, D-79104 Freiburg, Germany.
Science. 2011 Apr 1;332(6025):103-6. doi: 10.1126/science.1200660.
To optimize their growth and survival, plants perceive and respond to ultraviolet-B (UV-B) radiation. However, neither the molecular identity of the UV-B photoreceptor nor the photoperception mechanism is known. Here we show that dimers of the UVR8 protein perceive UV-B, probably by a tryptophan-based mechanism. Absorption of UV-B induces instant monomerization of the photoreceptor and interaction with COP1, the central regulator of light signaling. Thereby this signaling cascade controlled by UVR8 mediates UV-B photomorphogenic responses securing plant acclimation and thus promotes survival in sunlight.
为了优化其生长和生存，植物感知并响应紫外线-B（UV-B）辐射。然而，UV-B 光受体的分子身份和光感知机制尚不清楚。在这里，我们表明 UVR8 蛋白的二聚体感知 UV-B，可能通过色氨酸为基础的机制。UV-B 的吸收诱导光受体的瞬时单体化，并与 COP1 相互作用，COP1 是光信号的中央调节因子。因此，由 UVR8 介导的这种信号级联反应调控 UV-B 光形态建成反应，确保植物的适应能力，从而促进在阳光中的生存。
