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儿童金氏金杆菌性脊椎间盘炎:迈向细菌学调查的新方法?初步报告。

Kingella kingae spondylodiscitis in young children: toward a new approach for bacteriological investigations? A preliminary report.

作者信息

Ceroni Dimitri, Cherkaoui Abdessalam, Kaelin André, Schrenzel Jacques

出版信息

J Child Orthop. 2010 Apr;4(2):173-5. doi: 10.1007/s11832-009-0233-2. Epub 2010 Jan 10.

Abstract

As the result of improved bacteriological techniques, Kingella kingae is a slow-growing Gram-negative coccobacillus that is emerging as an important cause of spondylodiscitis in children younger than 3 years of age. The high pharyngeal carrier rates of this slow-growing Gram-negative coccobacillus combined with the low incidence of identified K. kingae infections is possibly explained by a low virulence of this bacterium. The use of specific real-time polymerase chain reaction (PCR) on blood samples and throat swabs opens new prospects in the bacteriological investigations of young children suspected to have spondylodiscitis, an approach that could prevent, in the future, unnecessary invasive interventions.

摘要

由于细菌学技术的改进,金氏金杆菌是一种生长缓慢的革兰氏阴性球杆菌,正成为3岁以下儿童脊椎骨髓炎的重要病因。这种生长缓慢的革兰氏阴性球杆菌的高咽部携带率,再加上已确诊的金氏金杆菌感染发病率较低,这可能是由于该细菌的低毒力所致。对血样和咽拭子进行特异性实时聚合酶链反应(PCR),为疑似患有脊椎骨髓炎的幼儿的细菌学调查开辟了新前景,这种方法未来可能会避免不必要的侵入性干预。

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