Department of Cardiologic, Thoracic and Vascular Sciences, 2nd Chair of Internal Medicine, University of Padua, Padua, Italy.
Semin Thromb Hemost. 2011 Apr;37(3):193-8. doi: 10.1055/s-0031-1273083. Epub 2011 Mar 31.
The role of gender in the causation of first and recurrent venous thromboembolism (VTE) is uncertain. The use of hormonal therapy and pregnancy has been associated with VTE in women. Epidemiological studies have described a higher incidence of first VTE in women of childbearing age. Nevertheless, no consistent differences in the overall incidence of VTE between males and females have been found. Recent studies have shown that women exhibit a lower risk of recurrent VTE than men, although these data were not confirmed in other studies that evaluated only women with idiopathic VTE. This article reviews the role of gender as a risk factor for first and recurrent VTE.
性别在首发和复发性静脉血栓栓塞症(VTE)中的作用尚不确定。激素治疗和妊娠与女性 VTE 相关。流行病学研究表明,生育年龄的女性首发 VTE 发生率更高。然而,男性和女性的 VTE 总体发生率并无一致差异。最近的研究表明,女性复发性 VTE 的风险低于男性,但这些数据在仅评估特发性 VTE 女性的其他研究中并未得到证实。本文综述了性别作为首发和复发性 VTE 的危险因素的作用。