离体大鼠心脏中的钙反常——地尔硫䓬的作用
Calcium paradox in the isolated rat-heart--the effects of diltiazem.
作者信息
Ravingerová T, Ziegelhöffer A, Tribulová N, Slezák J, Trégerová V
机构信息
Institute of Experimental Surgery, Slovak Academy of Sciences, Bratislava.
出版信息
Physiol Bohemoslov. 1990;39(3):253-6.
PMID:2145603
Abstract
The protective effect of calcium entry blockers can be studied advantageously on the model of the calcium paradox, particularly on the basis of the preservation of haemodynamic and biochemical parameters as well as on the structure of the myocardium (Meno et al. 1984). Our aim in this study was to test the protective effect of the recently developed Czechoslovak drug diltiazem (LACHEMA) under conditions of the Ca2+ paradox.
摘要
钙通道阻滞剂的保护作用可以在钙反常模型上进行有效研究，特别是基于血流动力学和生化参数的保持以及心肌结构（Meno等人，1984年）。本研究的目的是在Ca2+反常条件下测试最近开发的捷克斯洛伐克药物地尔硫卓（LACHEMA）的保护作用。
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