Hovendal C P, Rasmussen L, Pedersen S A
Kirurgisk afdeling K, Odense Sygehus.
Ugeskr Laeger. 1990 Oct 1;152(40):2926-7.
Between 1976 and 1988, 28 neonates with gastroschisis and 44 with omphalocele were treated. In 44 patients primary closure was achieved, while silastic prostheses were used in 23 patients, and dura implant in three patients. Two patients were not treated. The mortality rate was 8% (4/52) among the patients without serious congenital defects and birth weights over 1,800 g. This mortality was mainly caused by bowel infarction and, in infants with birth weights below 1,800 g, by the respiratory distress syndrome. Our experience suggests that ventilatory assistance with total paralysis is mandatory per- and postoperatively. The handling of these abdominal wall defects demands transport in an incubator with a nasogastric tube in place, a sterile bowel bag and replacement of fluid loss. Bowel stretch at the edge of the defect should be minimized in order to reduce the risk of bowel infarction. The favorable results of treatment of these malformations depend less on birth weight than on the presence of other serious congenital defects which are decisive for the mortality.
1976年至1988年间,对28例腹裂新生儿和44例脐膨出新生儿进行了治疗。44例患者实现了一期缝合,23例患者使用了硅橡胶假体,3例患者使用了硬脑膜植入物。2例患者未接受治疗。在无严重先天性缺陷且出生体重超过1800克的患者中,死亡率为8%(4/52)。这种死亡主要是由肠梗死引起的,而在出生体重低于1800克的婴儿中,主要是由呼吸窘迫综合征引起的。我们的经验表明,术前和术后必须进行完全瘫痪的通气辅助。处理这些腹壁缺损需要在保温箱中运送,放置鼻胃管,使用无菌肠袋并补充液体丢失。应尽量减少缺损边缘处肠管的拉伸,以降低肠梗死的风险。这些畸形治疗的良好结果与其说是取决于出生体重,不如说是取决于其他严重先天性缺陷的存在,而这些缺陷对死亡率起决定性作用。