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[糖尿病患者的围手术期管理]

[Perioperative management of diabetic patient].

作者信息

Carles Michel, Raucoules-Aimé Marc

机构信息

CHU de Nice, hôpital L'archet, service d'anesthésie-réanimation, 06200 Nice, France.

出版信息

Presse Med. 2011 Jun;40(6):587-95. doi: 10.1016/j.lpm.2011.01.017. Epub 2011 Mar 31.

Abstract

The prevalence of diabetes is rising and diabetics may soon represent more than 5% of the world population. The type 2 diabetes is a major independent risk factor for coronary artery disease. The screening for silent myocardial ischemia (IMS) must be systematic. The autonomic dysfunction and the cardiac microcirculatory disorders are at risk of hypotension and hypothermia during anesthesia. After 10 years of diabetes duration the incidence of perioperative complications and of difficult intubation are increased. The neurological deficits related to anesthesia are associated with general anesthesia in 85% of cases. Particular care will be provided during the surgical procedure to avoid skin, muscular and neurologic cuts. In most cases, the regional anesthesia will be preferred to general anesthesia. To avoid hypoglycemia, blood glucose concentration less than 11 mmol.L(-1)(2g.L(-1)) seems a reasonable target during and after surgery.

摘要

糖尿病的患病率正在上升,糖尿病患者可能很快将占世界人口的5%以上。2型糖尿病是冠状动脉疾病的主要独立危险因素。必须对无症状心肌缺血(IMS)进行系统筛查。自主神经功能障碍和心脏微循环障碍在麻醉期间有发生低血压和体温过低的风险。糖尿病病程达10年后,围手术期并发症和困难插管的发生率会增加。与麻醉相关的神经功能缺损在85%的病例中与全身麻醉有关。手术过程中会格外小心,以避免皮肤、肌肉和神经损伤。在大多数情况下,区域麻醉优于全身麻醉。为避免低血糖,手术期间及术后血糖浓度低于11 mmol.L⁻¹(2g.L⁻¹)似乎是一个合理的目标。

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