恙虫病东方体对宿主细胞信号的颠覆。
Subversion of host cell signaling by Orientia tsutsugamushi.
机构信息
Department of Immunology and Pathogen Biology, Tongji University School of Medicine, Shanghai 200092, China.
出版信息
Microbes Infect. 2011 Jul;13(7):638-48. doi: 10.1016/j.micinf.2011.03.003. Epub 2011 Mar 31.
PMID:21458586
Abstract
Progress has been made in deciphering the mechanisms on Orientia tsutsugamushi-host interaction. The genome sequencing, microarray and proteomic analyses of this ancient bacterium have provided a wealth of new information. This paper reviews the general characteristics of O. tsutsugamushi and recent developments especially in signaling events involved in the bacteria--host interaction.
摘要
在解析恙虫东方体与宿主相互作用的机制方面已经取得了进展。对这种古老细菌的基因组测序、微阵列和蛋白质组学分析提供了丰富的新信息。本文综述了恙虫东方体的一般特征和最新进展，特别是涉及细菌-宿主相互作用的信号事件。
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