[Clinical, diagnostic and therapeutic aspects of dermatophytosis].

Dermatophytes are a group of closely related fungi that have keratinase and can therefore cause infections in keratinised human and animal tissues (skin, hair and nails), leading to a disease known as dermatophytosis. This group is composed by the genera Epidermophyton, Trichophyton and Microsporum, forming an approximated total of 40 species. Depending on the source of the keratin used, dermatophytes can be divided in geophilic (soil), zoophilic (animals) and anthropophilic (human), with soil, some animals and humans being their primary habitats. Many dermatophytes can be present in both anamorphic (asexual state) or imperfect and teleomorphic state (with sexual reproduction) or perfect fungi. Anamorphic states (genera Epidermophyton, Microsporum and Trichophyton ) belong to the Hyphomycetes and phylum Deuteromycota class and teleomorphic states (the majority of geophilic and zoophilic species of Microsporum and Trichophyton) are classified in the teleomorphic genus Arthroderma, order Onygenales, phylum Ascomycota, and are usually found in their anamorphic state. Dermatophytes have a worldwide distribution, being responsible for most of the skin mycoses in both healthy and immunocompromised patients. The diagnosis and treatment of dermatophytosis are well known by most microbiologists and scientists in general. However, we describe recent techniques for their diagnosis and up-to-date treatments. The main purpose of this review is to provide a detailed description of the three genera of dermatophytes, with special mention of Epidermophyton floccosum, a object of the SEIMC's mycology quality control (M-2/09).