The Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania (Ms Chen, Dr Ruppert, Mr Noullet, Dr Zgibor)
The School of Nursing, University of Pittsburgh, Pennsylvania (Dr Charron-Prochownik)
Diabetes Educ. 2011 May-Jun;37(3):370-80. doi: 10.1177/0145721711400662. Epub 2011 Apr 1.
The purpose of this study was to examine the effects of depression and antidepressant use on goal setting and barrier identification in patients with type 2 diabetes.
In a large diabetes education network, 778 patients with type 2 diabetes were enrolled in the American Association of Diabetes Educators (AADE) Outcomes System as part of their routine diabetes education between 2005 and 2008. Self-reported depression, 7 self-identified behavior change goals, and 13 barriers to diabetes self-care were collected from the Diabetes Self-Management Assessment Report Tool (D-SMART(®)); antidepressant use was documented from the Diabetes Educator Tool (D-ET(®)). Multiple linear regression was used to evaluate the effects of depression or antidepressant use on the number of goals or the number of barriers while controlling for relevant covariates.
Among 778 patients (507 nondepressed, 181 depressed with antidepressant use, 90 depressed without antidepressant use), median age was 58, 60.9% were female, and 85.9% were Caucasian. Patients with and without depression had a similar number of self-identified behavior change goals, whereas patients with depression had 1 additional barrier to diabetes self-care compared with those without depression. In the depressed subgroup, antidepressant use had no association with the number of goals that the subjects set or the number of barriers they identified.
Among patients with type 2 diabetes, depression was associated with a slightly greater number of barriers, which may support the importance of depression screening and depression treatment in patients with diabetes.
本研究旨在探讨抑郁症和抗抑郁药物的使用对 2 型糖尿病患者目标设定和障碍识别的影响。
在美国糖尿病教育者协会(AADE)的糖尿病教育网络中,2005 年至 2008 年期间,778 名 2 型糖尿病患者参与了 AADE 结果系统(American Association of Diabetes Educators Outcomes System),作为其常规糖尿病教育的一部分。从糖尿病自我管理评估报告工具(Diabetes Self-Management Assessment Report Tool,D-SMART(®))中收集了自我报告的抑郁情况、7 个自我确定的行为改变目标以及 13 个糖尿病自我护理障碍;从糖尿病教育者工具(Diabetes Educator Tool,D-ET(®))中记录了抗抑郁药物的使用情况。采用多元线性回归分析评估抑郁或抗抑郁药物的使用对目标数量或障碍数量的影响,同时控制了相关协变量。
在 778 名患者中(507 名非抑郁,181 名抑郁伴抗抑郁药物治疗,90 名抑郁不伴抗抑郁药物治疗),患者的中位年龄为 58 岁,60.9%为女性,85.9%为白种人。抑郁和非抑郁患者自我确定的行为改变目标数量相似,但抑郁患者的糖尿病自我护理障碍比非抑郁患者多 1 个。在抑郁亚组中,抗抑郁药物的使用与患者设定的目标数量或识别的障碍数量之间没有关联。
在 2 型糖尿病患者中,抑郁与更多的障碍相关,这可能支持对糖尿病患者进行抑郁筛查和治疗的重要性。