Telomere G-overhang length measurement method 2: G-tail telomere HPA.

Both telomere length and telomere G-tail length are altered in human diseases such as cancer and -age-related disease. While most methods for the measurement of G-tail and telomere length require electrophoresis, centrifugation, radioisotope labeling, and autoradiography, G-tail telomere HPA provides a convenient and useful tool for the examination of G-tail length with a high-throughput platform using genomic DNA or cell lysate. G-tail telomere HPA may be applicable for clinical diagnostics as well as drug target screening.