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双侧同步扁桃体癌:病例系列及文献复习。

Bilateral synchronous tonsillar carcinoma: a case series and review of the literature.

机构信息

Colchester General Hospital, Turner Road, Colchester CO4 5JL, UK.

出版信息

Eur Arch Otorhinolaryngol. 2012 Jan;269(1):255-9. doi: 10.1007/s00405-011-1586-y. Epub 2011 Apr 3.

DOI:10.1007/s00405-011-1586-y
PMID:21461897
Abstract

We present the first dedicated case series of bilateral synchronous tonsillar carcinoma and discuss the role of bilateral tonsillectomy as a diagnostic tool. The occurrence of multiple head and neck tumours is well recognised; however, reports of bilateral synchronous tonsillar carcinoma are rare. A literature review reveals only 12 cases of bilateral synchronous tonsillar carcinoma described in the international literature in the past 15 years. We present a further three cases confirmed following bilateral tonsillectomy. In conclusion, bilateral tonsillectomy has in many centres been established as a standard diagnostic and therapeutic procedure for patients who have cervical metastases from a head and neck cancer of unknown primary site. It is likely the true incidence of bilateral synchronous tonsillar carcinoma is underestimated and under-reported. We recommend bilateral tonsillectomy for patients with suspected or proven unilateral tonsillar carcinoma as well as those with cervical metastases from unknown primary site.

摘要

我们提出了首例双侧扁桃体癌的专门病例系列,并讨论了双侧扁桃体切除术作为诊断工具的作用。 众所周知,头部和颈部的多种肿瘤的发生是很常见的;但是,双侧扁桃体癌的报道却很少。文献回顾显示,在过去的 15 年中,国际文献中仅描述了 12 例双侧扁桃体癌。我们又报告了另外 3 例经双侧扁桃体切除术证实的病例。总之,在许多中心,双侧扁桃体切除术已被确立为标准的诊断和治疗程序,适用于那些因不明原发灶的头颈部癌症而出现颈部转移的患者。双侧扁桃体癌的真实发病率可能被低估和漏报。我们建议对疑似或确诊的单侧扁桃体癌患者以及因不明原发灶而出现颈部转移的患者进行双侧扁桃体切除术。

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Bilateral synchronous tonsillar carcinoma: a case series and review of the literature.双侧同步扁桃体癌:病例系列及文献复习。
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引用本文的文献

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Synchronous bilateral tonsil carcinoma: case presentation and review of the literature.同步双侧扁桃体癌:病例报告及文献综述
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Severe prolonged dysphagia following transoral resection of bilateral synchronous tonsillar carcinoma.

本文引用的文献

1
Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site.对来源于头颈部不明原发灶的鳞状细胞癌转移至颈部淋巴结的诊断评估。
Laryngoscope. 2009 Dec;119(12):2348-54. doi: 10.1002/lary.20638.
2
[The rare case of simultaneous bilateral cancer of tonsilla palatina with large metastases to lymphoid glands of the neck].
Otolaryngol Pol. 2007;61(4):501-4. doi: 10.1016/s0030-6657(07)70470-5.
3
Role of tonsillectomy in the search for a squamous cell carcinoma from an unknown primary in the head and neck.扁桃体切除术在头颈部不明原发灶鳞状细胞癌排查中的作用
经口切除双侧同步性扁桃体癌后出现严重的长期吞咽困难。
Eur Arch Otorhinolaryngol. 2015 Nov;272(11):3585-91. doi: 10.1007/s00405-015-3540-x. Epub 2015 Feb 8.
Br J Oral Maxillofac Surg. 2008 Jun;46(4):283-7. doi: 10.1016/j.bjoms.2007.11.017. Epub 2008 Feb 20.
4
Case-control study of human papillomavirus and oropharyngeal cancer.人乳头瘤病毒与口咽癌的病例对照研究
N Engl J Med. 2007 May 10;356(19):1944-56. doi: 10.1056/NEJMoa065497.
5
Trends in palatine tonsillar cancer incidence and mortality rates in the United States.美国腭扁桃体癌发病率和死亡率的趋势。
Community Dent Oral Epidemiol. 2007 Apr;35(2):98-108. doi: 10.1111/j.1600-0528.2007.00299.x.
6
Synchronous bilateral tonsillar carcinoma: role of fluoro-deoxyglucose positron emission tomography scanning in detecting occult primary tumours in metastatic nodal disease of the head and neck.同步双侧扁桃体癌:氟脱氧葡萄糖正电子发射断层扫描在检测头颈部转移性淋巴结疾病中隐匿性原发肿瘤的作用
J Laryngol Otol. 2006 Apr;120(4):334-7. doi: 10.1017/S0022215106000260.
7
Bilateral synchronous tonsillar carcinoma in cervical cancer of unknown primary site (CUPS).双侧同步扁桃体癌在原发部位不明的宫颈癌(CUPS)中。
Eur Arch Otorhinolaryngol. 2003 Oct;260(9):490-3. doi: 10.1007/s00405-003-0590-2. Epub 2003 May 9.
8
Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study.烟草与酒精对喉癌风险的联合影响:一项病例对照研究。
Cancer Causes Control. 2002 Dec;13(10):957-64. doi: 10.1023/a:1021944123914.
9
Human papillomavirus type 16 and squamous cell carcinoma of the head and neck.人乳头瘤病毒16型与头颈部鳞状细胞癌
Clin Cancer Res. 2002 Oct;8(10):3187-92.
10
Nutrition and pharyngeal cancer: results from a case-control study in Spain.营养与咽癌:西班牙一项病例对照研究的结果
Head Neck. 2002 Sep;24(9):830-40. doi: 10.1002/hed.10142.