Department of Radiology, College of Medicine, Lagos State University, Ikeja, Lagos, Nigeria.
Psychooncology. 2012 Jun;21(6):675-9. doi: 10.1002/pon.1968. Epub 2011 Apr 3.
While the physical complications of breast cancer are often recognized and well managed, the psychological sequelae, especially depression are often unrecognized by healthcare providers and therefore under treated. This study aimed to assess the rate and correlate of depressive disorders in breast cancer survivors in Lagos, Nigeria.
Patients (n = 124) recruited from a breast cancer outpatient clinic were assessed for the DSM-IV diagnosis of depressive disorders using the Mini International Neuropsychiatric Interview (MINI). The staging of the cancer, length of diagnosis and treatment type were recorded. Also socio-demographic details and their perceived level of social support were obtained.
Twenty-one (16.9%) were diagnosed as having Major Depressive Disorder, while 29 (23.4%) had Minor depressive disorder making a total of 50 (40.3%) cases with depression. The independent correlates of depression included being not married (odds ratio (OR) 3.09, 95% CI 1.30-7.42), perceived poor social support (OR 5.38, 95% CI 1.88-16.63) and advanced stage of the cancer (OR 3.22, 95% CI 1.32-8.26).
Our study suggests a high rate of associated depression among patients with breast cancer in our environment. Clinicians should be encouraged and empowered to probe for symptoms of depression in these patient while larger hypothesis-driven studies are needed.
虽然乳腺癌的身体并发症经常被认识到并得到很好的治疗，但心理后遗症，特别是抑郁症，经常被医疗保健提供者忽视，因此治疗不足。本研究旨在评估尼日利亚拉各斯乳腺癌幸存者中抑郁障碍的发生率和相关性。
从乳腺癌门诊招募了 124 名患者，使用 Mini International Neuropsychiatric Interview (MINI) 评估 DSM-IV 诊断的抑郁障碍。记录癌症分期、诊断和治疗类型的长度。还获得了社会人口统计学细节及其感知的社会支持水平。
21 名（16.9%）被诊断为患有重度抑郁症，29 名（23.4%）患有轻度抑郁症，共有 50 名（40.3%）患有抑郁症。抑郁的独立相关因素包括未婚（比值比（OR）3.09，95%可信区间 1.30-7.42）、感知社会支持差（OR 5.38，95%可信区间 1.88-16.63）和癌症晚期（OR 3.22，95%可信区间 1.32-8.26）。
我们的研究表明，在我们的环境中，乳腺癌患者中存在较高的抑郁相关率。应鼓励和授权临床医生在这些患者中探查抑郁症状，同时需要进行更大的假设驱动研究。
