West Nicholas P, Quirke Philip, Hagemann-Madsen Rikke Hjarnø
Pathology & Tumour Biology, Leeds Institute of Molecular Medicine,St James' University Hospital, Leeds, England.
Ugeskr Laeger. 2011 Apr 4;173(14):1037-40.
Colorectal cancer is common in the Western world and is a leading cause of cancer related mortality. The introduction of multidisciplinary teams and focus on quality control has led to improved outcomes in which pathologists play a central role through feedback to surgeons, radiologists, and oncologists. This review focuses on the importance of pathological examination of the resection specimen and subsequent feedback to the surgical team regarding quality. Specific markers of oncological quality including grading the plane of surgery, tissue morphometry and lymph node yields are discussed.
结直肠癌在西方世界很常见,是癌症相关死亡的主要原因。多学科团队的引入以及对质量控制的关注已带来了更好的治疗结果,其中病理学家通过向外科医生、放射科医生和肿瘤内科医生提供反馈发挥着核心作用。本综述重点关注切除标本病理检查的重要性以及随后就质量问题向手术团队提供反馈。讨论了肿瘤学质量的具体指标,包括手术切缘分级、组织形态测量和淋巴结收获情况。