Laboratoire CEPERC, UMR CNRS, 6059, Université de Provence, France.
Prog Biophys Mol Biol. 2011 Aug;106(2):348-52. doi: 10.1016/j.pbiomolbio.2011.03.006. Epub 2011 Apr 2.
In this essay we examine whether a theoretical and conceptual framework for systems biology could be built from the Bailly and Longo (2008, 2009) proposal. These authors aim to understand life as a coherent critical structure, and propose to develop an extended physical approach of evolution, as a diffusion of biomass in a space of complexity. Their attempt leads to a simple mathematical reconstruction of Gould's assumption (1989) concerning the bacterial world as a "left wall of least complexity" that we will examine. Extended physical systems are characterized by their constructive properties. Time is acting and new properties emerge by their history that can open the list of their initial properties. This conceptual and theoretical framework is nothing more than a philosophical assumption, but as such it provides a new and exciting approach concerning the evolution of life, and the transition between physics and biology.
在本文中,我们探讨了 Bailly 和 Longo(2008 年,2009 年)的提议是否可以为系统生物学构建一个理论和概念框架。这些作者旨在将生命理解为一个连贯的临界结构,并提议开发一种扩展的物理进化方法,即将生物量扩散到复杂性空间中。他们的尝试导致了对古尔德假设(1989 年)的简单数学重构,我们将对此进行考察。扩展的物理系统的特征是其建设性属性。时间在起作用,新的属性通过其历史出现,这可以打开其初始属性的列表。这个概念和理论框架只不过是一个哲学假设,但作为一个哲学假设,它为生命进化以及物理学和生物学之间的过渡提供了一种新的、令人兴奋的方法。