Pharmacy and Therapeutics, Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA.
Nicotine Tob Res. 2011 Jun;13(6):466-73. doi: 10.1093/ntr/ntr026. Epub 2011 Apr 4.
We examined prescribing patterns for nicotine replacement therapies (NRTs) in a large psychiatric hospital, before and after the implementation of a smoking ban.
We extracted 5 years of NRT utilization data from hospital pharmacy records. The ban went into effect on January 1, 2007. Data reflect NRT prescriptions from 2 years before and 3 years after the ban, and N = 30,908 total inpatient hospital admissions.
The monthly rate of total NRT prescriptions increased after the ban from M = 254.25 (SD = 126.60) doses per month to M = 4,467.52 (SD = 1,785.87) doses per month (>1,700% increase, p < .0001). After the smoking ban, clinicians prescribed higher doses of transdermal (but not oral) NRT (Tukey, p < .0001). Comparisons of NRT prescribing across hospital units tentatively suggested that patients being treated on the substance use disorders unit were prescribed more doses of NRT, as well as higher doses of NRT compared with patients on other units. Analysis of trends over time showed no apparent downward trend for NRT usage during the 3 years following the smoking ban, suggesting that clinicians continued to treat nicotine dependence after smoking was restricted.
Clinicians are more likely to identify and treat symptoms of nicotine withdrawal when smoking is restricted. Hospitals should consider monitoring prescriptions for NRT as part of their ongoing quality assurance practices so that patients receive aggressive treatment of nicotine withdrawal symptoms--an essential component of high-quality patient care.
在一家大型精神病医院禁烟令实施前后,我们研究了尼古丁替代疗法(NRT)的处方模式。
我们从医院药房记录中提取了 5 年的 NRT 使用数据。该禁令于 2007 年 1 月 1 日生效。数据反映了禁令实施前 2 年和实施后 3 年的 NRT 处方情况,共有 30908 例住院患者。
禁令实施后,每月总 NRT 处方量从 M = 254.25(SD = 126.60)剂/月增加到 M = 4467.52(SD = 1785.87)剂/月(增加>1700%,p<.0001)。在禁烟令之后,临床医生开出了更高剂量的透皮(而非口服)NRT(Tukey,p<.0001)。对不同医院科室的 NRT 处方进行比较,初步表明在物质使用障碍科治疗的患者开出的 NRT 剂量更高,与其他科室的患者相比,NRT 剂量也更高。对随时间变化的趋势进行分析表明,在禁烟令实施后的 3 年内,NRT 的使用并没有明显下降的趋势,这表明临床医生在限制吸烟后继续治疗尼古丁依赖。
当吸烟受到限制时,临床医生更有可能识别和治疗尼古丁戒断症状。医院应考虑将 NRT 处方监测作为其持续质量保证实践的一部分,以确保患者接受尼古丁戒断症状的积极治疗——这是高质量患者护理的重要组成部分。