Umenai T, Sasaki T, Konno T
Tohoku J Exp Med. 1977 Jul;122(3):299-300. doi: 10.1620/tjem.122.299.
Antibacterial activity could be detected in bacterium-negative duodenal juice from 3 patients, whereas it was not detected in bacterium-positive duodenal juice from other 3 patients. The follow-up study revealed that appearance of the activity in duodenal juice was just coincident with disappearance of bacteria in duodenal juice. The activity was not influenced by pH of the duodenal juice. These results seem to suggest that some antibacterial activity, different from that of pH, in duodenal juice regulates in some way proliferation of the upper gastrointestinal flora.
在3例患者的细菌阴性十二指肠液中可检测到抗菌活性，而在其他3例患者的细菌阳性十二指肠液中未检测到。随访研究显示，十二指肠液中该活性的出现恰好与十二指肠液中细菌的消失同时发生。该活性不受十二指肠液pH值的影响。这些结果似乎表明，十二指肠液中存在某种不同于pH值的抗菌活性，它以某种方式调节上消化道菌群的增殖。
