Kierat Andrzej, Laszczyńska Maria, Kowalska Elzbieta, Weyna Elzbieta
Katedra i Zakład Stomatologii Ogólnej Pomorskiej Akademii Medycznej w Szczecinie al. Powstańców Wlkp. 72, 70-111 Szczecin.
Ann Acad Med Stetin. 2010;56(2):89-96.
The aim of this study was to evaluate the usefulness of a new product called Mineral Trioxide Aggregate (MTA) used in direct and indirect pulp capping. The results of pulp treatment using therapeutic MTA with the results after application of calcium hydroxide were compared. Moreover, the aim of the study was to determine the toxicity of the investigated materials in relation to human fibroblast cultures derived from dental pulp.
The study included 97 patients, male and female in the age 8-56 years. A total of 135 vital pulp therapy treatments were performed. Depending on the material and methods, the patients were assigned to four groups.
In the carried out study 88.2% of the results were positive after a direct coverage of the pulp using MTA and 86.7% of positive results were after the application of calcium hydroxide. In the case of indirect use of both the MTA and Ca(OH)2 100% positive results were obtained. Biocompatibility test preparations showed significantly lower toxicity of MTA compared with Ca(OH)2.
On the basis of clinical examination Mineral trioxide Aggregate proved to be as effective as calcium hydroxide in the direct and indirect pulp capping. It has been shown that the deeper damage to the pulp, of the kind during its injury, worse the prognosis compared to an exposure in the pulp. Mineral Trioxide Aggregate proved to be highly statistically significantly less toxic compared to Ca(OH)2.
本研究的目的是评估一种名为三氧化矿物凝聚体(MTA)的新产品在直接和间接盖髓中的应用效果。将使用治疗性MTA进行牙髓治疗的结果与应用氢氧化钙后的结果进行比较。此外,该研究的目的是确定所研究材料对源自牙髓的人成纤维细胞培养物的毒性。
该研究纳入了97名年龄在8至56岁之间的男女患者。共进行了135次活髓治疗。根据材料和方法,将患者分为四组。
在本研究中,使用MTA直接覆盖牙髓后,88.2%的结果为阳性,应用氢氧化钙后86.7%的结果为阳性。在间接使用MTA和Ca(OH)2的情况下,均获得了100%的阳性结果。生物相容性测试制剂显示,与Ca(OH)2相比,MTA的毒性显著更低。
根据临床检查,三氧化矿物凝聚体在直接和间接盖髓方面与氢氧化钙一样有效。结果表明,牙髓损伤时损伤越深,与牙髓暴露相比预后越差。与Ca(OH)2相比,三氧化矿物凝聚体的毒性在统计学上显著更低。