Department for Cranio- and Maxillofacial Surgery of Heinrich Heine University Düsseldorf, Moorenstr. 5 (Geb. 18.73), D-40225 Düsseldorf, Germany.
In Vivo. 2011 Mar-Apr;25(2):283-6.
Bleeding disorders (BD) can cause significant problems during or after surgical procedures of the oral cavity. The aim of this study was to explore the risk of bleeding following oral surgery in patients with BD.
The medical records of all BD patients referred to the department of cranio- and maxillofacial surgery were reviewed.
Ninety-five patients (26 inherent BD, 69 taking antithrombotic drugs) were reviewed for this study. Interestingly, patients taking oral anticoagulants presented more bleeding complications than patients with inherent BD. During simple tooth extraction procedures, patients taking antithrombotic drugs had a higher risk of bleeding than patients with inherent BD.
The currently available treatment protocols for surgical treatment of dental patients with inherent BD suffice. However, our data indicates that there is still a need for clear guidelines for the treatment of patients taking antithrombotic drugs, especially phenprocoumon.
出血性疾病 (BD) 可导致口腔手术期间或之后出现严重问题。本研究旨在探讨 BD 患者口腔手术后出血的风险。
回顾了所有转至颅颌面外科的 BD 患者的病历。
本研究共回顾了 95 例患者（26 例为固有 BD，69 例服用抗血栓药物）。有趣的是，服用口服抗凝剂的患者比固有 BD 患者更容易出现出血并发症。在简单的拔牙手术中，服用抗血栓药物的患者出血风险高于固有 BD 患者。
目前针对固有 BD 牙科患者手术治疗的治疗方案已经足够。然而，我们的数据表明，仍需要针对服用抗血栓药物（尤其是苯丙香豆素）的患者制定明确的治疗指南。
