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恐惧回避信念对腰椎功能障碍患者治疗后风险调整功能状态结果预测模型的影响。

Effect of fear-avoidance beliefs of physical activities on a model that predicts risk-adjusted functional status outcomes in patients treated for a lumbar spine dysfunction.

机构信息

Focus On Therapeutic Outcomes, Inc, 551 Yopps Cove Road, White Stone, VA 22578, USA.

出版信息

J Orthop Sports Phys Ther. 2011 May;41(5):336-45. doi: 10.2519/jospt.2011.3534. Epub 2011 Apr 6.

Abstract

STUDY DESIGN

Retrospective analysis of a prospective, longitudinal cohort study of 30 858 patients being treated for a lumbar spine dysfunction in outpatient physical therapy.

OBJECTIVES

To determine effect of adding a single-item screening variable classifying patients with elevated versus not-elevated scores of fear-avoidance beliefs of physical activities at intake, on a model predicting risk-adjusted functional status (FS) outcomes.

BACKGROUND

Outcomes must be risk-adjusted before making meaningful interpretations. Elevated fear-avoidance beliefs scores have been predictive of poor outcomes. But the importance of elevated fear-avoidance scores in a multivariable model predicting FS outcomes needs further study.

METHODS

Using retrospective analyses, predictive ability (R2) of multivariable linear regression models of discharge FS with and without classification by elevated versus not-elevated fear-avoidance scores were compared, while controlling for intake FS, age, symptom acuity, surgical history, gender, number of comorbidities, and payer. Percent variance controlled and beta coefficients (95% confidence intervals) of each variable in both models were compared. A split-half design was used for model cross-validation. Predictive ratios (predicted FS, divided by actual discharge FS) were assessed.

RESULTS

Adding fear-avoidance beliefs classification to the discharge FS model improved (P<.001) model predictive ability but only slightly (R2 without, and with, fear-avoidance classification, 0.2997 and 0.3010, respectively). Variables impacted models similarly (95% confidence intervals not different). Fear-avoidance classification added 0.2% data variance control to the existing model. Cross-validation was supported. Predictive ratios were 1.09 and 1.10, without and with fear-avoidance, respectively.

CONCLUSION

Although screening for elevated fear-avoidance beliefs of physical activities significantly improves the FS outcomes predictive model, the amount of additional meaningful interpretation of FS outcomes was minimal. Exploration of other clinically relevant variables designed to improve outcomes prediction is warranted.

LEVEL OF EVIDENCE

Prognosis, level 2c.

摘要

研究设计

对 30858 名在门诊物理治疗中治疗腰椎功能障碍的前瞻性纵向队列研究进行回顾性分析。

目的

确定在预测风险调整功能状态 (FS) 结果的模型中,添加一个单项筛选变量来分类患者在摄入时的恐惧回避信念活动评分升高与不升高,对模型的效果。

背景

在进行有意义的解释之前,必须对结果进行风险调整。升高的恐惧回避信念评分一直是不良结果的预测指标。但是,在预测 FS 结果的多变量模型中,升高的恐惧回避评分的重要性需要进一步研究。

方法

使用回顾性分析,比较在控制摄入 FS、年龄、症状严重程度、手术史、性别、合并症数量和支付方的情况下,具有和不具有升高的恐惧回避评分分类的出院 FS 多变量线性回归模型的预测能力 (R2)。比较两个模型中每个变量的方差控制百分比和β系数 (95%置信区间)。使用半分割设计进行模型交叉验证。评估预测比(预测 FS 除以实际出院 FS)。

结果

将恐惧回避信念分类添加到出院 FS 模型中提高了模型预测能力(P<.001),但只是略有提高(无恐惧回避分类和有恐惧回避分类的 R2 分别为 0.2997 和 0.3010)。变量对模型的影响相似(95%置信区间没有差异)。恐惧回避分类为现有模型增加了 0.2%的数据方差控制。交叉验证得到支持。预测比分别为 1.09 和 1.10,无恐惧回避和有恐惧回避。

结论

尽管对身体活动的恐惧回避信念进行筛查可显著改善 FS 结果的预测模型,但对 FS 结果的解释意义不大。需要探索其他旨在改善结果预测的临床相关变量。

证据水平

预后,2c 级。

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