Department of Ophthalmology and Otolaryngology, Bari University, Italy.
Eye Contact Lens. 2011 Nov;37(6):374-6. doi: 10.1097/ICL.0b013e3182128e93.
To report a case of sympathetic ophthalmia (SO) after a severe Acanthamoeba keratitis.
METHODS/DESIGN: Interventional case report.
A 59-year-old white woman, wearing contact lenses, developed a severe Acanthamoeba keratitis in the left eye, which involved the limbus, and required 8 months of intensive antiamoeba therapy; the condition resolved leaving a painful, phthisical eye with complete corneal neovascularization. Six months later, the patient presented with pain, blurred vision, and photophobia in the right eye. Slitlamp examination of the right eye revealed granulomatous uveitis. On the suspicion of an SO, treatment with high-dose topical and oral corticosteroids and immunosuppressants was started. After 3 months, the eye is stable, with a visual acuity of 20/50, and the patient is taking prednisolone 7.5 mg per day and cyclophosphamide 50 mg per day.
[corrected] Development of SO in the absence of previous trauma or surgery is rare. Our case is the first report of a clinically diagnosed SO after an episode of severe Acanthamoeba keratitis.
报告一例棘阿米巴角膜炎后发生交感眼炎（SO）的病例。
方法/设计：介入性病例报告。
一名 59 岁白人女性，戴隐形眼镜，左眼发生严重棘阿米巴角膜炎，累及角膜缘，需要 8 个月的强化抗阿米巴治疗；病情缓解后遗留疼痛、病眼、完全性角膜新生血管化。6 个月后，患者右眼出现疼痛、视力模糊和畏光。右眼裂隙灯检查显示肉芽肿性葡萄膜炎。鉴于怀疑为 SO，开始使用大剂量局部和口服皮质类固醇和免疫抑制剂治疗。3 个月后，眼睛稳定，视力为 20/50，患者每天服用泼尼松龙 7.5 毫克和环磷酰胺 50 毫克。
[已纠正]在没有既往创伤或手术的情况下发生 SO 极为罕见。我们的病例是首例临床诊断的棘阿米巴角膜炎后发生的 SO 报告。
