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进食障碍的死亡率:1974 年至 2000 年在专科病房治疗的随访研究。

Mortality of eating disorders: a follow-up study of treatment in a specialist unit 1974-2000.

机构信息

Department of Neuroscience, Child and Adolescent Psychiatry, Uppsala University Hospital, Uppsala, Sweden.

出版信息

Int J Eat Disord. 2011 May;44(4):304-10. doi: 10.1002/eat.20827.

Abstract

OBJECTIVE

To study excess mortality, causes of death, and co-morbidity in patients with eating disorder (ED), treated in a Swedish specialist facility.

METHOD

A retrospective cohort study of 201 patients with ED followed from 1974 to year 2001 in the Swedish Causes of Death Register (SCODR). Standardized mortality ratio (SMR) was calculated with respect to the Swedish population, by gender, age, and calendar time.

RESULTS

In the complete follow-up of 201 patients, 23 had died. At a mean follow-up of 14.3 years the overall SMR was 10. Patients with body mass index (BMI) over 11.5 had an average SMR of about 7 and for those with BMI lower than 11.5 had SMR above 30. Six patients died from AN/starvation, nine due to suicide, and eight from other causes.

DISCUSSION

SMR in anorexia nervosa (AN) is high but not in bulimia nervosa. A risk stratification of AN, based on BMI is suggested.

摘要

目的

研究在瑞典专门机构接受治疗的饮食失调(ED)患者的超额死亡率、死亡原因和合并症。

方法

这是一项对 201 名 ED 患者的回顾性队列研究,这些患者在瑞典死因登记册(SCODR)中于 1974 年至 2001 年进行了随访。根据性别、年龄和日历时间,用标准化死亡率(SMR)计算了瑞典人口的死亡率。

结果

在对 201 名患者的完整随访中,有 23 人死亡。在平均 14.3 年的随访中,总 SMR 为 10。体重指数(BMI)超过 11.5 的患者平均 SMR 约为 7,而 BMI 低于 11.5 的患者 SMR 高于 30。6 名患者死于神经性厌食症(AN)/饥饿,9 名患者自杀,8 名患者死于其他原因。

讨论

神经性厌食症(AN)的 SMR 较高,但神经性贪食症(BN)则不然。建议根据 BMI 对 AN 进行风险分层。

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