Duke Clinical Research, Durham, NC, USA.
Am Heart J. 2011 Apr;161(4):746-54. doi: 10.1016/j.ahj.2011.01.012.
Black and Hispanic populations are at increased risk for developing heart failure (HF) at a younger age and experience differential morbidity and possibly differential mortality compared with whites. Yet, there have been insufficient data characterizing the clinical presentation, quality of care, and outcomes of patients hospitalized with HF as a function of race/ethnicity.
We analyzed 78,801 patients from 257 hospitals voluntarily participating in the American Heart Association's Get With The Guidelines-HF Program from January 2005 thru December 2008. There were 56,266 (71.4%) white, 17,775 (22.6%) black, and 4,760 (6.0%) Hispanic patients. In patients hospitalized with HF, we sought to assess clinical characteristics, adherence to core and other guideline-based HF care measures, and in-hospital mortality as a function of race and ethnicity.
Relative to white patients, Hispanic and black patients were significantly younger (median age 78.0, 63.0, 64.0 years, respectively), had lower left ventricular ejection fractions, and had more diabetes mellitus and hypertension. With few exceptions, the provision of guideline-based care was comparable for black, Hispanic, and white patients. Black and Hispanic patients had lower in-hospital mortality than white patients: black/white odds ratio 0.69, 95% CI 0.62-0.78, P < .001 and Hispanic/white odds ratio 0.81, 95% CI 0.67-0.98, P = .03.
Hispanic and black patients hospitalized with HF have more cardiovascular risk factors than white patients; however; they have similar or better in-hospital mortality rates. Within the context of a national HF quality improvement program, HF care was equitable and improved in all racial/ethnic groups over time.
黑人和西班牙裔人群在较年轻时患心力衰竭(HF)的风险增加,与白人相比,他们的发病率和死亡率可能存在差异。然而,目前还缺乏足够的数据来描述因种族/民族而异的心力衰竭住院患者的临床表现、护理质量和结局。
我们分析了 2005 年 1 月至 2008 年 12 月期间自愿参加美国心脏协会的 Get With The Guidelines-HF 计划的 257 家医院的 78801 名患者。其中 56266 名(71.4%)为白人,17775 名(22.6%)为黑人,4760 名(6.0%)为西班牙裔。在因 HF 住院的患者中,我们试图评估临床特征、对核心和其他基于指南的 HF 护理措施的依从性以及住院死亡率与种族和民族的关系。
与白人患者相比,西班牙裔和黑人患者明显更年轻(中位数年龄分别为 78.0、63.0 和 64.0 岁),左心室射血分数较低,且糖尿病和高血压的发病率较高。除了少数例外,黑人、西班牙裔和白人患者接受基于指南的护理的情况相当。黑人/白人患者住院死亡率较低:黑人/白人比值比为 0.69,95%可信区间为 0.62-0.78,P<.001;西班牙裔/白人比值比为 0.81,95%可信区间为 0.67-0.98,P=0.03。
因 HF 住院的西班牙裔和黑人患者比白人患者有更多的心血管危险因素;然而,他们的住院死亡率相似或更低。在国家 HF 质量改进计划的背景下,随着时间的推移,所有种族/民族群体的 HF 护理质量都得到了提高。