Knowlton Amy R, Yang Cui, Bohnert Amy, Wissow Lawrence, Chander Geetanjali, Arnsten Julia A
Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
AIDS Care. 2011 Sep;23(9):1102-10. doi: 10.1080/09540121.2011.554516. Epub 2011 May 24.
Compared to US men, US women have worse HAART and HIV health outcomes. The study examined main partner factors associated with women's HAART adherence. The community sample comprised 85% African-Americans; 63% had a main partner and 32% relied on their partner for emotional support. Adherence was highest (92%) among those without a main partner and lowest (57%) among those with an HIV seropositive main partner. In adjusted analysis, adherence was 75% less likely among women with an HIV seropositive main partner and 78% less likely among those relying on their partner for emotional support. Furthermore, HIV seropositive versus other serostatus main partners were most likely to provide medication taking assistance and to be preferred in helping participants deal with HIV, yet were no more likely to be nominated as the most helpful to them. Findings reveal women's perceived unmet support needs from HIV seropositive main partners in this population and the need for interventions to promote their HAART adherence. Seroconcordant couples-focused intervention that enhances mutual support of HAART adherence may be an effective approach to improving women's HAART adherence and reducing US gender disparities in HIV health outcomes.
与美国男性相比，美国女性接受高效抗逆转录病毒治疗（HAART）的情况以及艾滋病毒健康状况更差。该研究调查了与女性HAART依从性相关的主要伴侣因素。社区样本中85%为非裔美国人；63%有主要伴侣，32%依靠伴侣给予情感支持。在没有主要伴侣的人群中依从性最高（92%），而在主要伴侣艾滋病毒血清呈阳性的人群中依从性最低（57%）。在调整分析中，主要伴侣艾滋病毒血清呈阳性的女性依从性降低的可能性为75%，依靠伴侣给予情感支持的女性依从性降低的可能性为78%。此外，艾滋病毒血清呈阳性的伴侣与其他血清状况的主要伴侣相比，最有可能提供服药帮助，并且在帮助参与者应对艾滋病毒方面更受青睐，但被提名为对她们最有帮助的可能性并无差异。研究结果揭示了该人群中女性认为艾滋病毒血清呈阳性主要伴侣未满足其支持需求的情况，以及需要采取干预措施来提高她们的HAART依从性。以血清学一致的伴侣为重点的干预措施，增强对HAART依从性的相互支持，可能是提高女性HAART依从性并减少美国艾滋病毒健康状况方面性别差异的有效方法。
