Vernon H J, Olsen E A
Department of Medicine, Duke University Medical Center, Durham, NC 27710.
J Am Acad Dermatol. 1990 Nov;23(5 Pt 1):829-32. doi: 10.1016/0190-9622(90)70297-u.
We studied the effectiveness of clobetasol propionate ointment 0.05% in experimentally induced Rhus dermatitis. Clobetasol rapidly decreased the vesiculation at each treated site, although the effect was most prominent at the site to which clobetasol was applied the earliest, that is, at 12 hours after exposure to Rhus extract. On the basis of this experimental model, clobetasol propionate ointment 0.05% may be effective therapy for naturally occurring Rhus dermatitis.
我们研究了0.05%丙酸氯倍他索软膏对实验性诱导的漆树皮炎的疗效。丙酸氯倍他索能迅速减少每个治疗部位的水疱形成,尽管在最早涂抹丙酸氯倍他索的部位,即接触漆树提取物后12小时的部位,效果最为显著。基于此实验模型,0.05%丙酸氯倍他索软膏可能是治疗自然发生的漆树皮炎的有效疗法。