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孕期饮食模式与产后抑郁风险:希腊克里特岛的“Rhea”母婴队列研究。

Dietary patterns during pregnancy and the risk of postpartum depression: the mother-child 'Rhea' cohort in Crete, Greece.

机构信息

Department of Social Medicine, Faculty of Medicine, University of Crete, PO Box 2208, Heraklion 71003, Crete, Greece.

出版信息

Public Health Nutr. 2011 Sep;14(9):1663-70. doi: 10.1017/S1368980010003629. Epub 2011 Apr 11.

DOI:10.1017/S1368980010003629
PMID:21477412
Abstract

OBJECTIVE

To identify and describe dietary patterns in a cohort of pregnant women, and investigate whether dietary patterns during pregnancy are related to postpartum depression (PPD).

DESIGN

The study uses data from the prospective mother-child cohort 'Rhea' study. Pregnant women completed an FFQ in mid-pregnancy and the Edinburg Postpartum Depression Scale (EPDS) at 8-10 weeks postpartum. Dietary patterns during pregnancy ('health conscious', 'Western') were identified using principal component analysis. Associations between dietary patterns categorized in tertiles and PPD symptoms were investigated by multivariable regression models after adjusting for confounders.

SETTING

Heraklion, Crete, Greece, 2007-2010.

SUBJECTS

A total of 529 women, participating in the 'Rhea' cohort.

RESULTS

High adherence to a 'health conscious' diet, characterized by vegetables, fruit, pulses, nuts, dairy products, fish and olive oil, was associated with lower EPDS scores (highest v. lowest tertile: β-coefficient = -1·75, P = 0·02). Women in the second (relative risk (RR) = 0·52, 95 % CI 0·30, 0·92) or third tertile (RR = 0·51, 95 % CI 0·25, 1·05) of the 'health conscious' dietary pattern were about 50 % less likely to have high levels of PPD symptoms (EPDS ≥ 13) compared with those in the lowest tertile.

CONCLUSIONS

This is the first prospective study showing that a healthy diet during pregnancy is associated with reduced risk for PPD. Additional longitudinal studies and trials are needed to confirm these findings.

摘要

目的

识别和描述孕妇队列中的饮食模式,并研究怀孕期间的饮食模式是否与产后抑郁症(PPD)有关。

设计

本研究使用前瞻性母婴队列“Rhea”研究的数据。孕妇在妊娠中期完成了一份食物频率问卷,并在产后 8-10 周时使用爱丁堡产后抑郁量表(EPDS)进行了评估。使用主成分分析确定了妊娠期间的饮食模式(“健康意识型”、“西式”)。在调整混杂因素后,通过多变量回归模型研究了饮食模式分类为三分位与 PPD 症状之间的关系。

地点

希腊克里特岛的伊拉克利翁,2007-2010 年。

对象

共有 529 名参加“Rhea”队列的女性。

结果

高依从“健康意识型”饮食,其特征为蔬菜、水果、豆类、坚果、奶制品、鱼类和橄榄油,与 EPDS 评分较低相关(最高与最低三分位数相比:β系数=-1·75,P=0·02)。处于“健康意识型”饮食模式第二(相对风险(RR)=0·52,95%置信区间 0·30,0·92)或第三三分位(RR=0·51,95%置信区间 0·25,1·05)的女性与处于最低三分位的女性相比,发生 PPD 症状(EPDS≥13)的可能性低约 50%。

结论

这是第一项表明怀孕期间健康饮食与降低 PPD 风险相关的前瞻性研究。需要进一步的纵向研究和试验来证实这些发现。

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