Clinics CDPI and Multi-Imagem, Rua Saddock de Sá 266, Rio de Janeiro, Brazil; Clinic IRM, Rua Capitao Salomao 44, Rio de Janeiro, Brazil; Department of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Neuroimaging Clin N Am. 2011 Feb;21(1):71-88, vii-viii. doi: 10.1016/j.nic.2011.02.006.
Multiple sclerosis (MS) is considered the most common inflammatory autoimmune neurologic disorder and the most frequent cause of nontraumatic neurologic disability in young and middle-age adults. This article reviews the basic features of its magnetic resonance (MR) imaging lesions and, primarily, the use of diffusion MR imaging, which is increasingly applied to assess patients with MS, not only to investigate plaques but also the normal-appearing white matter, gray matter, optic nerve, and spinal cord, because of its ability to detect and quantify disease-related pathologic conditions of the central nervous system.
多发性硬化症（MS）被认为是最常见的炎症性自身免疫性神经疾病，也是中青年人群非外伤性神经功能障碍的最常见原因。本文回顾了其磁共振成像（MR）病变的基本特征，主要讨论了扩散 MR 成像的应用，该技术越来越多地用于评估 MS 患者，不仅用于研究斑块，还用于研究正常表现的白质、灰质、视神经和脊髓，因为它能够检测和量化中枢神经系统的疾病相关病理状况。
