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利用生物动力学和剂量学模型评估室内氡子体吸入剂量及其在约旦人群中的应用。

Inhalation dose assessment of indoor radon progeny using biokinetic and dosimetric modeling and its application to Jordanian population.

机构信息

Helmholtz Zentrum München, German Research Center for Environmental Health, Department of Medical Radiation Physics and Diagnostics, Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany.

出版信息

J Environ Radioact. 2011 Jun;102(6):574-80. doi: 10.1016/j.jenvrad.2011.03.003. Epub 2011 Apr 8.

Abstract

High indoor radon concentrations in Jordan result in internal exposures of the residents due to the inhalation of radon and its short-lived progeny. It is therefore important to quantify the annual effective dose and further the radiation risk to the radon exposure. This study describes the methodology and the biokinetic and dosimetric models used for calculation of the inhalation doses exposed to radon progeny. The regional depositions of aerosol particles in the human respiratory tract were firstly calculated. For the attached progeny, the activity median aerodynamic diameters of 50 nm, 230 nm and 2500 nm were chosen to represent the nucleation, accumulation and coarse modes of the aerosol particles, respectively. For the unattached progeny, the activity median thermodynamic diameter of 1 nm was chosen to represent the free progeny nuclide in the room air. The biokinetic models developed by the International Commission on Radiological Protection (ICRP) were used to calculate the nuclear transformations of radon progeny in the human body, and then the dosimetric model was applied to estimate the organ equivalent doses and the effective doses with the specific effective energies derived from the mathematical anthropomorphic phantoms. The dose conversion coefficient estimated in this study was 15 mSv WLM(-1) which was in the range of the values of 6-20 mSv WLM(-1) reported by other investigators. Implementing the average indoor radon concentration in Jordan, the annual effective doses were calculated to be 4.1 mSv y(-1) and 0.08 mSv y(-1) due to the inhalation of radon progeny and radon gas, respectively. The total annual effective dose estimated for Jordanian population was 4.2 mSv y(-1). This high annual effective dose calculated by the dosimetric approach using ICRP biokinetic and dosimetric models resulted in an increase of a factor of two in comparison to the value by epidemiological study. This phenomenon was presented by the ICRP in its new published statement on radon.

摘要

高浓度的室内氡会导致约旦居民吸入氡及其短寿命子体而受到内照射。因此,量化氡暴露的年有效剂量和进一步评估辐射风险非常重要。本研究描述了用于计算吸入氡子体剂量的方法以及生物动力学和剂量学模型。首先计算了气溶胶粒子在人体呼吸道中的区域沉积。对于附着的子体,选择 50nm、230nm 和 2500nm 的活性中值空气动力学直径分别代表气溶胶粒子的成核、积累和粗模态。对于非附着的子体,选择 1nm 的活性中值热动力学直径代表室内空气中的自由子体核素。国际辐射防护委员会(ICRP)开发的生物动力学模型用于计算氡子体在人体中的核转化,然后应用剂量学模型,利用从数学人体模型得出的特定有效能量来估算器官当量剂量和有效剂量。本研究估计的剂量转换系数为 15mSvWLM(-1),处于其他研究者报告的 6-20mSvWLM(-1)范围内。采用约旦室内氡的平均值,由于吸入氡子体和氡气,年有效剂量分别计算为 4.1mSv y(-1)和 0.08mSv y(-1)。约旦人口的总年有效剂量估计为 4.2mSv y(-1)。与流行病学研究相比,采用 ICRP 生物动力学和剂量学模型的剂量学方法计算得出的高年有效剂量增加了一倍,这一现象在 ICRP 关于氡的新发表声明中得到了阐述。

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